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O-GlcNAcylation at the tumor–immune interface: a metabolic post-translational code driving immune evasion and therapy resistance in cancer

Protein O-GlcNAcylation has evolved from a metabolic curiosity into a master post-translational modification that enables cancer cells to translate nutrient availability into coordinated programs of proliferation, therapy resistance, and immune evasion. In this review, we argue that hyper-O-GlcNAcyl...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Shanshan Liu, Peng Zhan, WenJie Tian, Jinning Gu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2026-07-01
Schriftenreihe:Frontiers in Immunology
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1854952/full
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