Immunization-induced antigen archiving enhances local memory CD8+ T cell responses following an unrelated viral infection

Abstract Antigens from viruses or immunizations can persist or are archived in lymph node stromal cells such as lymphatic endothelial cells (LEC) and fibroblastic reticular cells (FRC). Here, we find that, during the time frame of antigen archiving, LEC apoptosis caused by a second, but unrelated, i...

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Ngā kaituhi matua:	Thu A. Doan, Tadg S. Forward, Johnathon B. Schafer, Erin D. Lucas, Ira Fleming, Aspen Uecker-Martin, Edgardo Ayala, Jenna J. Guthmiller, Jay R. Hesselberth, Thomas E. Morrison, Beth A. Jirón Tamburini
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Nature Portfolio 2024-03-01
Rangatū:	npj Vaccines
Urunga tuihono:	https://doi.org/10.1038/s41541-024-00856-6
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!

Immunization-induced antigen archiving enhances local memory CD8+ T cell responses following an unrelated viral infection

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