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Immunization-induced antigen archiving enhances local memory CD8+ T cell responses following an unrelated viral infection

Abstract Antigens from viruses or immunizations can persist or are archived in lymph node stromal cells such as lymphatic endothelial cells (LEC) and fibroblastic reticular cells (FRC). Here, we find that, during the time frame of antigen archiving, LEC apoptosis caused by a second, but unrelated, i...

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Xehetasun bibliografikoak
Egile Nagusiak: Thu A. Doan, Tadg S. Forward, Johnathon B. Schafer, Erin D. Lucas, Ira Fleming, Aspen Uecker-Martin, Edgardo Ayala, Jenna J. Guthmiller, Jay R. Hesselberth, Thomas E. Morrison, Beth A. Jirón Tamburini
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Portfolio 2024-03-01
Saila:npj Vaccines
Sarrera elektronikoa:https://doi.org/10.1038/s41541-024-00856-6
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