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Deep gray matter atrophy mediates the associations between glymphatic dysfunction and clinical disability in relapsing-remitting multiple sclerosis: a neuroimaging subgroup study

BackgroundImpaired glymphatic function is linked to cerebral atrophy and contributes to clinical disability in patients with relapsing-remitting multiple sclerosis (RRMS). Deep gray matter volume (DGMV) loss is associated with disability; however, its mediating effect in MS-related disability and gl...

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Hlavní autoři: Hao Zhang, Ruisi Gong, Hefei Fu, Jinlin Jiao, Mengyao Li, Zixuan Song, Ziying Zhang, Yueluan Jiang, Ye Han, Feng Shi, Jibin Cao, Lingling Cui
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2026-03-01
Edice:Frontiers in Immunology
Témata:
deep gray matter volume
DTI along the perivascular space
DTI-ALPS
glymphatic function
multiple sclerosis
On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1758859/full
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