Targeting natural splicing plasticity of APOBEC3B restricts its expression and mutagenic activity
A. Rouf Banday et al. report targeting alternative splicing of APOBEC3B as a strategy to modulate APOBEC-mediated mutagenesis in cancers. Higher expression of the mutagenic APOBEC3B isoform predicted shorter progression-free survival in bladder cancer patients. Expression of this mutagenic isoform c...
I tiakina i:
| Ngā kaituhi matua: | , , , , , , , , , , , , |
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| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
Nature Portfolio
2021-03-01
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| Rangatū: | Communications Biology |
| Urunga tuihono: | https://doi.org/10.1038/s42003-021-01844-5 |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
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