DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis

Breast cancer genomes have revealed a novel form of mutation showers (kataegis) in which multiple same-strand substitutions at C:G pairs spaced one to several hundred nucleotides apart are clustered over kilobase-sized regions, often associated with sites of DNA rearrangement. We show kataegis can r...

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Váldodahkkit:	Benjamin JM Taylor, Serena Nik-Zainal, Yee Ling Wu, Lucy A Stebbings, Keiran Raine, Peter J Campbell, Cristina Rada, Michael R Stratton, Michael S Neuberger
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	eLife Sciences Publications Ltd 2013-04-01
Ráidu:	eLife
Fáttát:	Hypermutation DNA deamination AID/APOBEC Kataegis Cancer Cytidine deamination
Liŋkkat:	https://elifesciences.org/articles/00534
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