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ML241 Antagonizes ERK 1/2 Activation and Inhibits Rotavirus Proliferation

Rotavirus (RV) is the main pathogen that causes severe diarrhea in infants and children under 5 years of age. No specific antiviral therapies or licensed anti-rotavirus drugs are available. It is crucial to develop effective and low-toxicity anti-rotavirus small-molecule drugs that act on novel host...

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Principais autores: Jinlan Wang, Xiaoqing Hu, Jinyuan Wu, Xiaochen Lin, Rong Chen, Chenxing Lu, Xiaopeng Song, Qingmei Leng, Yan Li, Xiangjing Kuang, Jinmei Li, Lida Yao, Xianqiong Tang, Jun Ye, Guangming Zhang, Maosheng Sun, Yan Zhou, Hongjun Li
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2024-04-01
coleção:Viruses
Assuntos:
rotavirus
ML241 (hydrochloride)
MAPK signaling pathway
ERK1/2
NF-κB
Acesso em linha:https://www.mdpi.com/1999-4915/16/4/623
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