ML241 Antagonizes ERK 1/2 Activation and Inhibits Rotavirus Proliferation

Rotavirus (RV) is the main pathogen that causes severe diarrhea in infants and children under 5 years of age. No specific antiviral therapies or licensed anti-rotavirus drugs are available. It is crucial to develop effective and low-toxicity anti-rotavirus small-molecule drugs that act on novel host...

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Principais autores:	Jinlan Wang, Xiaoqing Hu, Jinyuan Wu, Xiaochen Lin, Rong Chen, Chenxing Lu, Xiaopeng Song, Qingmei Leng, Yan Li, Xiangjing Kuang, Jinmei Li, Lida Yao, Xianqiong Tang, Jun Ye, Guangming Zhang, Maosheng Sun, Yan Zhou, Hongjun Li
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2024-04-01
Serija:	Viruses
Teme:	rotavirus ML241 (hydrochloride) MAPK signaling pathway ERK1/2 NF-κB
Online dostop:	https://www.mdpi.com/1999-4915/16/4/623
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