Towards a Safer, More Randomized Lentiviral Vector Integration Profile Exploring Artificial LEDGF Chimeras.
The capacity to integrate transgenes into the host cell genome makes retroviral vectors an interesting tool for gene therapy. Although stable insertion resulted in successful correction of several monogenic disorders, it also accounts for insertional mutagenesis, a major setback in otherwise success...
Salvato in:
| Autori principali: | , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science (PLoS)
2016-01-01
|
| Serie: | PLoS ONE |
| Accesso online: | http://europepmc.org/articles/PMC5082951?pdf=render |
| Tags: |
Nessun Tag, puoi essere il primo ad aggiungerne!!
|