BET-independent MLV-based Vectors Target Away From Promoters and Regulatory Elements
Stable integration in the host genome renders murine leukemia virus (MLV)-derived vectors attractive tools for gene therapy. Adverse events in otherwise successful clinical trials caused by proto-oncogene activation due to vector integration hamper their application. MLV and MLV-based vectors integr...
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| Principais autores: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Elsevier
2014-01-01
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| Serija: | Molecular Therapy: Nucleic Acids |
| Online dostop: | http://www.sciencedirect.com/science/article/pii/S2162253116303201 |
| Oznake: |
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