Preliminary evaluation of the toxicological, antioxidant and antitumor activities promoted by the compounds 2,4-dihydroxy-benzylidene-thiosemicarbazones an in silico, in vitro and in vivo study

Abstract Thiosemicarbazones are promising classes of compounds with antitumor activity. For this study, six 2,4-dihydroxy-benzylidene-thiosemicarbazones compounds were synthesized. These compounds were submitted to different assays in silico, in vitro and in vivo to evaluate the toxicological, antio...

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Κύριοι συγγραφείς:	MAYSE MANUELE F.V. LEAL, MARIA FERNANDA DA SILVA, DIEGO SANTA CLARA MARQUES, RAUDINEY FRANKILIN V. MENDES, RAFAEL M. XIMENES, DIJANAH C. MACHADO, JANILSON JOSÉ DA SILVA JÚNIOR, CLÁUDIO GABRIEL RODRIGUES, IRANILDO JOSÉ DA CRUZ FILHO, MARIA DO CARMO A. DE LIMA
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Academia Brasileira de Ciências 2024-05-01
Σειρά:	Anais da Academia Brasileira de Ciências
Θέματα:	antioxidant antitumor cytotoxicity sarcoma 180 thiosemicarbazones
Διαθέσιμο Online:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652024000200604&lng=en&tlng=en
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