Preliminary evaluation of the toxicological, antioxidant and antitumor activities promoted by the compounds 2,4-dihydroxy-benzylidene-thiosemicarbazones an in silico, in vitro and in vivo study

Abstract Thiosemicarbazones are promising classes of compounds with antitumor activity. For this study, six 2,4-dihydroxy-benzylidene-thiosemicarbazones compounds were synthesized. These compounds were submitted to different assays in silico, in vitro and in vivo to evaluate the toxicological, antio...

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Váldodahkkit:	MAYSE MANUELE F.V. LEAL, MARIA FERNANDA DA SILVA, DIEGO SANTA CLARA MARQUES, RAUDINEY FRANKILIN V. MENDES, RAFAEL M. XIMENES, DIJANAH C. MACHADO, JANILSON JOSÉ DA SILVA JÚNIOR, CLÁUDIO GABRIEL RODRIGUES, IRANILDO JOSÉ DA CRUZ FILHO, MARIA DO CARMO A. DE LIMA
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Academia Brasileira de Ciências 2024-05-01
Ráidu:	Anais da Academia Brasileira de Ciências
Fáttát:	antioxidant antitumor cytotoxicity sarcoma 180 thiosemicarbazones
Liŋkkat:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652024000200604&lng=en&tlng=en
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