Biological sex and age influence GS-9620 activity ex vivo
Toll-like receptors (TLRs) are being explored to enhance immunity in HIV cure strategies. The TLR7 agonist GS-9620 promotes immune activation, reactivates latent HIV, and delays viral rebound in some people with HIV. Previous work has shown that biological sex influences TLR7 signaling. This study e...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical investigation
2025-06-01
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| Col·lecció: | JCI Insight |
| Matèries: | |
| Accés en línia: | https://doi.org/10.1172/jci.insight.182242 |
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