A method for measuring mitochondrial DNA copy number in pediatric populations

The mitochondrion is a multifunctional organelle that modulates multiple systems critical for homeostasis during pathophysiological stress. Variation in mitochondrial DNA (mtDNA) copy number (mtDNAcn), a key mitochondrial change associated with chronic stress, is an emerging biomarker for disease pa...

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Bibliographic Details

Main Authors:	Simran Maggo, Liam Y. North, Aime Ozuna, Dejerianne Ostrow, Yander R. Grajeda, Hesamedin Hakimjavadi, Jennifer A. Cotter, Alexander R. Judkins, Pat Levitt, Xiaowu Gai
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2024-06-01
Series:	Frontiers in Pediatrics
Subjects:	mitochondrial DNA copy number adversity lpWGS adverse childhood experience (ACE) DNA RNA extraction
Online Access:	https://www.frontiersin.org/articles/10.3389/fped.2024.1401737/full
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