Intranasal Delivery of Granisetron to the Brain via Nanostructured Cubosomes-Based In Situ Gel for Improved Management of Chemotherapy-Induced Emesis

This research aimed to boost granisetron (GS) delivery to the brain via the intranasal route to better manage chemotherapy-induced emesis. Glycerol monooleate (GMO), Poloxamer 407 (P 407) and Tween 80 (T 80) were used to formulate GS-loaded cubosomes (GS-CBS) utilizing a melt dispersion-emulsificati...

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Ngā taipitopito rārangi puna kōrero

Ngā kaituhi matua:	Essam M. Eissa, Mohammed H. Elkomy, Hussein M. Eid, Adel A. Ali, Mohammed A. S. Abourehab, Amal M. Alsubaiyel, Ibrahim A. Naguib, Izzeddin Alsalahat, Amira H. Hassan
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	MDPI AG 2022-06-01
Rangatū:	Pharmaceutics
Ngā marau:	granisetron cubosomes in situ gel biodistribution brain targeting pharmacokinetics
Urunga tuihono:	https://www.mdpi.com/1999-4923/14/7/1374
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!