Autoradiography of 3H-pirenzepine and 3H-AFDX-384 in Mouse Brain Regions: Possible Insights into M1, M2, and M4 Muscarinic Receptors Distribution

Autoradiography helps to determine the distribution and density of muscarinic receptor (MR) binding sites in the brain. However, it relies on the selectivity of radioligands toward their target. 3H-Pirenzepine is commonly believed to label predominantly M1MR, 3H-AFDX-384 is considered as M2MR select...

תיאור מלא

מידע ביבליוגרפי

Principais autores:	Paulina Valuskova, Vladimir Farar, Sandor Forczek, Iva Krizova, Jaromir Myslivecek
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2018-02-01
סדרה:	Frontiers in Pharmacology
נושאים:	M1 muscarinic receptor M2 muscarinic receptor M4 muscarinic receptor 3H-pirenzepine 3H-AFDX-384 3H-QNB
גישה מקוונת:	http://journal.frontiersin.org/article/10.3389/fphar.2018.00124/full
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!