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4-Arylthiosemicarbazide derivatives as a new class of tyrosinase inhibitors and anti-Toxoplasma gondii agents

We report herein anti-proliferation effects of 4-arylthiosemicarbazides, with a cyclopentane substitution at N1 position, on highly virulent RH strain of Toxoplasma gondii. Among them, the highest in vitro anti-Toxoplasma activity was found with the meta-iodo derivative. Further experiments demonstr...

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Autors principals: Adrian Bekier, Lidia Węglińska, Agata Paneth, Piotr Paneth, Katarzyna Dzitko
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis Group 2021-01-01
Col·lecció:Journal of Enzyme Inhibition and Medicinal Chemistry
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Accés en línia:http://dx.doi.org/10.1080/14756366.2021.1931164
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