Discovery of Potent and Selective Halogen-Substituted Imidazole-Thiosemicarbazides for Inhibition of <i>Toxoplasma gondii</i> Growth In Vitro via Structure-Based Design
Employing a simple synthetic protocol, a series of highly effective halogen-substituted imidazole-thiosemicarbazides with anti-<i>Toxoplasma gondii</i> effects against the RH tachyzoites, much better than sulfadiazine, were obtained (IC<sub>50s</sub> 10.30—113.45 µg/mL vs. ~2721.45 µ...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
MDPI AG
2019-04-01
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| Seri Bilgileri: | Molecules |
| Konular: | |
| Online Erişim: | https://www.mdpi.com/1420-3049/24/8/1618 |
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