SENP2 regulates UCP1-dependent thermogenesis in brown adipocytes via deSUMOylation of ERRα
Abstract Brown adipose tissue (BAT) is responsible for energy homeostasis and adaptive thermogenesis. SUMO-specific protease 2 (SENP2) plays an essential role in adipogenesis; however, the role of SENP2 in BAT metabolism has not been explored. Here we investigated the role of SENP2 in mature brown a...
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| Principais autores: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2025-06-01
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| Serier: | Experimental and Molecular Medicine |
| Online adgang: | https://doi.org/10.1038/s12276-025-01458-5 |
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