Role of enterocyte Enpp2 and autotaxin in regulating lipopolysaccharide levels, systemic inflammation, and atherosclerosis

Conversion of lysophosphatidylcholine to lysophosphatidic acid (LPA) by autotaxin, a secreted phospholipase D, is a major pathway for producing LPA. We previously reported that feeding Ldlr−/− mice standard mouse chow supplemented with unsaturated LPA or lysophosphatidylcholine qualitatively mimicke...

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Auteurs principaux:	Arnab Chattopadhyay, Pallavi Mukherjee, Dawoud Sulaiman, Huan Wang, Victor Girjalva, Nasrin Dorreh, Jonathan P. Jacobs, Samuel Delk, Wouter H. Moolenaar, Mohamad Navab, Srinivasa T. Reddy, Alan M. Fogelman
Format:	Artigo
Langue:	Inglês
Publié:	Elsevier 2023-05-01
Collection:	Journal of Lipid Research
Sujets:	lysophospholipase D lysophosphatidic acid atherosclerosis oxidized phospholipids small intestine apolipoprotein A-I mimetic peptides
Accès en ligne:	http://www.sciencedirect.com/science/article/pii/S0022227523000433
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