Models for prediction of single base primer extension efficiency from position and type of single mismatch in primer-template duplex

Amplification and specificity of polymerase chain reaction (PCR) are affected by the position and type of primer-template mismatches (MMs) as well as various conditions of reaction. In this study, multiple linear regression (MLR) models and artificial neural network (ANN) models were developed for t...

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Автори:	Myong-Rim Ri, Jin-Sok Kang, Myong-Ryong Ri, Song Nam U
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Elsevier 2023-08-01
Серія:	Heliyon
Предмети:	Multiple linear regression models Artificial neural network models Single base extension
Онлайн доступ:	http://www.sciencedirect.com/science/article/pii/S2405844023060371
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