Increased expression of miR146a dysregulates TLR2-induced HBD2 in airway epithelial cells from patients with COPD

Background Airway epithelial cells from patients with COPD show suboptimal innate immune responses to nontypeable Haemophilus influenzae (NTHi) and Toll-like receptor (TLR)2 ligands despite expressing TLR2 similar to normal airway epithelial cells, but the underlying mechanisms are poorly understood...

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Hauptverfasser:	Hymavathi Reddy-Vari, Yerin Kim, Charu Rajput, Umadevi S. Sajjan
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	European Respiratory Society 2023-05-01
Schriftenreihe:	ERJ Open Research
Online-Zugang:	http://openres.ersjournals.com/content/9/3/00694-2022.full
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