Increased expression of miR146a dysregulates TLR2-induced HBD2 in airway epithelial cells from patients with COPD
Background Airway epithelial cells from patients with COPD show suboptimal innate immune responses to nontypeable Haemophilus influenzae (NTHi) and Toll-like receptor (TLR)2 ligands despite expressing TLR2 similar to normal airway epithelial cells, but the underlying mechanisms are poorly understood...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
European Respiratory Society
2023-05-01
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| coleção: | ERJ Open Research |
| Acesso em linha: | http://openres.ersjournals.com/content/9/3/00694-2022.full |
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