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O-fucosylation of DLL3 is required for its function during somitogenesis.

Delta-like 3 (DLL3) is a member of the DSL family of Notch ligands in amniotes. In contrast to DLL1 and DLL4, the other Delta-like proteins in the mouse, DLL3 does not bind in trans to Notch and does not activate the receptor, but shows cis-interaction and cis-inhibitory properties on Notch signalin...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Katrin Serth, Karin Schuster-Gossler, Elisabeth Kremmer, Birte Hansen, Britta Marohn-Köhn, Achim Gossler
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Public Library of Science (PLoS) 2015-01-01
Rangatū:PLoS ONE
Urunga tuihono:http://europepmc.org/articles/PMC4391858?pdf=render
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