MAPT Mutations V337M and N297K Alter Organelle Trafficking in Frontotemporal Dementia Patient-Specific Motor Neurons

Frontotemporal dementia (FTD) is a neurodegenerative disease characterized by the progressive loss of neurons mainly in the frontal and temporal lobes of the brain. Mutations (e.g., V337M, N297K) in the microtubule-associated protein TAU (MAPT) are responsible 5–20% of familial FTD cases and have be...

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Egile Nagusiak:	Christiane Hartmann, Marie Anskat, Marc Ehrlich, Jared Sterneckert, Arun Pal, Andreas Hermann
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	MDPI AG 2024-03-01
Saila:	Biomedicines
Gaiak:	FTD MAPT TAU organelle trafficking mitochondria lysosome
Sarrera elektronikoa:	https://www.mdpi.com/2227-9059/12/3/641
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