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Propionic Acid, Induced in Gut by an Inulin Diet, Suppresses Inflammation and Ameliorates Liver Ischemia and Reperfusion Injury in Mice

Liver ischemia and reperfusion injury (IRI) is one of the obstacles in liver surgery such as liver resection and transplantation. In this study, we investigated the preventive effect on mouse liver IRI by feeding mice with inulin, which is a heterogeneous blend of indigestible fructose polymer. Mice...

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Principais autores: Junya Kawasoe, Yoichiro Uchida, Hiroshi Kawamoto, Tomoyuki Miyauchi, Takeshi Watanabe, Kenichi Saga, Kosuke Tanaka, Shugo Ueda, Hiroaki Terajima, Kojiro Taura, Etsuro Hatano
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2022-04-01
Serier:Frontiers in Immunology
Fag:
liver ischemia-reperfusion injury
inulin diet
short-chain fatty acid
gut microbiota
propionic acid
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2022.862503/full
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