Melittin restores proteasome function in an animal model of ALS

<p>Abstract</p> <p>Amyotrophic lateral sclerosis (ALS) is a paralyzing disorder characterized by the progressive degeneration and death of motor neurons and occurs both as a sporadic and familial disease. Mutant SOD1 (mtSOD1) in motor neurons induces vulnerability to the disease through protein misf...

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Principais autores:	Lee Sang Min, Yang Sun Choel, Kim Seon Hwy, Yang Eun Jin, Choi Sun-Mi
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2011-06-01
Serija:	Journal of Neuroinflammation
Teme:	hSOD1<sup>G93A</sup> Melittin Amyotrophic lateral sclerosis (ALS) α-synuclein
Online dostop:	http://www.jneuroinflammation.com/content/8/1/69
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