Lead exposure induces ferroptosis in ALS cell models by activating the MAPK/ERK signaling pathway

Lead is a potent toxicant that exerts deleterious effects on multiple organ systems within the human body. Existing evidence suggests that lead exposure may contribute to the progression of amyotrophic lateral sclerosis (ALS). However, the precise mechanism remains unclear and the experimental evide...

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Autori principali:	Yi Gao, Bingxue Zheng, Xiaoxiao Peng, Nanxin Ma, Yan Qi, Xiaodie Lan, Ying Wang, Hongyan Zha, Chu Zhou, Fuying Liu, Qian Zhao, Hongyan Cao, Li Wang, Yulan Qiu, Jinping Zheng, Jian Guo
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2025-11-01
Serie:	Ecotoxicology and Environmental Safety
Soggetti:	Lead Amyotrophic lateral sclerosis hSOD1G93A Ferroptosis MAPK/ERK
Accesso online:	http://www.sciencedirect.com/science/article/pii/S014765132501646X
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