TET proteins regulate T cell and iNKT cell lineage specification in a TET2 catalytic dependent manner

TET proteins mediate DNA demethylation by oxidizing 5-methylcytosine to 5-hydroxymethylcytosine (5hmC) and other oxidative derivatives. We have previously demonstrated a dynamic enrichment of 5hmC during T and invariant natural killer T cell lineage specification. Here, we investigate shared signatu...

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Hlavní autoři:	Tarmo Äijö, Dimitris Theofilatos, Meng Cheng, Matthew D. Smith, Yue Xiong, Albert S. Baldwin, Ageliki Tsagaratou
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2022-08-01
Edice:	Frontiers in Immunology
Témata:	TET proteins Th-POK DNA Methylation 5hmC lineage specification
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.940995/full
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