Comparison of Genotype Imputation for SNP Array and Low-Coverage Whole-Genome Sequencing Data

Genotype imputation is the term used to describe the process of inferring unobserved genotypes in a sample of individuals. It is a key step prior to a genome-wide association study (GWAS) or genomic prediction. The imputation accuracy will directly influence the results from subsequent analyses. In...

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Hlavní autoři:	Tianyu Deng, Pengfei Zhang, Dorian Garrick, Huijiang Gao, Lixian Wang, Fuping Zhao
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2022-01-01
Edice:	Frontiers in Genetics
Témata:	genotype imputation SNP density reference population size imputation accuracy SNP chip sequencing
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fgene.2021.704118/full
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