Validation of circulating miR-323a-3p and miR-625-3p to classify hypertrophic cardiomyopathy in Friedreich’s ataxia

Abstract Friedreich’s ataxia (FRDA) is an inherited neurodegenerative disorder frequently complicated by hypertrophic cardiomyopathy (HCM), a major cause of morbidity and mortality in these patients. Conventional protein biomarkers, such as high-sensitivity troponin or collagen turnover markers, pro...

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Hauptverfasser:	José Santiago Ibáñez-Cabellos, Raquel Baviera-Muñoz, Berta Alemany-Perna, Rafael Sivera, Luis Bataller, Sergio Cesar, Pilar González-Cabo, José Luis García-Giménez, Federico V. Pallardó, Marta Seco-Cervera
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2026-05-01
Schriftenreihe:	Scientific Reports
Schlagworte:	Epigenetics FRDA MiRNAs Biomarkers Cardiopathy
Online-Zugang:	https://doi.org/10.1038/s41598-026-50975-4
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