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TP53-mutated myelodysplastic syndromes and acute myeloid leukemia: a comprehensive overview of targeted approaches

TP53-mutated acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) represent a biologically and clinically distinct subset of myeloid malignancies characterized by poor prognosis, resistance to standard therapies, and high rates of relapse. TP53 mutations, particularly biallelic are frequ...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Shweta Deshpande, Wing Fai Li, Junmin Song, Mark Forsberg, Claudio Cerchione, Giovanni Martinelli, Marina Konopleva
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2026-02-01
Cyfres:Frontiers in Oncology
Pynciau:
Mynediad Ar-lein:https://www.frontiersin.org/articles/10.3389/fonc.2026.1735418/full
Tagiau: Ychwanegu Tag
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