Prognostic heterogeneity and clonal dynamics within distinct subgroups of myelodysplastic syndrome and acute myeloid leukemia with TP53 disruptions

Abstract TP53 aberrations constitute the highest risk subset of myelodysplastic neoplasms (MDS) and acute myeloid leukemia (AML). The International Consensus Classification questions the blast threshold between MDS and AML. In this study, we assess the distinction between MDS and AML for 76 patients...

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Autori principali:	Shyam A. Patel, Jan Cerny, William K. Gerber, Muthalagu Ramanathan, Asiri Ediriwickrema, Benjamin Tanenbaum, Lloyd Hutchinson, Xiuling Meng, Julie Flahive, Bruce Barton, Andrew J. Gillis‐Smith, Sakiko Suzuki, Salwa Khedr, William Selove, Anne W. Higgins, Patricia M. Miron, Karl Simin, Bruce Woda, Jonathan M. Gerber
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wiley 2023-11-01
Serie:	eJHaem
Soggetti:	TP53 myelodysplastic syndrome acute myeloid leukemia hematopoietic stem cell clonal dynamics
Accesso online:	https://doi.org/10.1002/jha2.791
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