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CRISPR screening in hematology research: from bulk to single-cell level

Abstract The CRISPR genome editing technology has revolutionized the way gene function is studied. Genome editing can be achieved in single genes or for thousands of genes simultaneously in sensitive genetic screens. While conventional genetic screens are limited to bulk measurements of cell behavio...

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Autori principali: Sarah Meyers, Sofie Demeyer, Jan Cools
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2023-10-01
Serie:Journal of Hematology & Oncology
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Accesso online:https://doi.org/10.1186/s13045-023-01495-5
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