Mitotic progression, arrest, exit or death relies on centromere structural integrity, rather than de novo transcription

Recent studies have challenged the prevailing dogma that transcription is repressed during mitosis. Transcription was also proposed to sustain a robust spindle assembly checkpoint (SAC) response. Here, we used live-cell imaging of human cells, RNA-seq and qPCR to investigate the requirement for de n...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Marco Novais-Cruz, Maria Alba Abad, Wilfred FJ van IJcken, Niels Galjart, A Arockia Jeyaprakash, Helder Maiato, Cristina Ferrás
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	eLife Sciences Publications Ltd 2018-08-01
Σειρά:	eLife
Θέματα:	mitosis transcription spindle assembly checkpoint Aurora B kinetochore centromere
Διαθέσιμο Online:	https://elifesciences.org/articles/36898
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