Adenine Ribonucleotide (AXP) Depletion Due to Inherited Deficiency of Adenosine Deaminase 1 (ADA)
Adenosine deaminase 1-deficient severe combined immune deficiency (ADA-SCID) has widely been attributed to the toxic accumulation of adenine deoxyribonucleotides (dAXP) derived from 2’-deoxyadenosine (dAdo). The presence of dAXP in red blood cells (RBC) is pathognomonic, and higher dAXP levels track...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Rockefeller University Press
2026-05-01
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| Serie: | Journal of Human Immunity |
| Accesso online: | https://rupress.org/jhi/article/2/CIS2026/eCIS2026abstract.26/282008/Adenine-Ribonucleotide-AXP-Depletion-Due-to |
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