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RETRACTED: Synergistic antitumor effects of novel HDAC inhibitors and paclitaxel in vitro and in vivo.

Preclinical studies support the therapeutic potential of histone deacetylases inhibitors (HDACi) in combination with taxanes. The efficacy of combination has been mainly ascribed to a cooperative effect on microtubule stabilization following tubulin acetylation. In the present study we investigated...

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Autors principals: Valentina Zuco, Michelandrea De Cesare, Raffaella Cincinelli, Raffaella Nannei, Claudio Pisano, Nadia Zaffaroni, Franco Zunino
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2011-01-01
Col·lecció:PLoS ONE
Accés en línia:https://doi.org/10.1371/journal.pone.0029085
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