Update on the Discovery of Efflux Pump Inhibitors against Critical Priority Gram-Negative Bacteria

Antimicrobial resistance (AMR) has become a major problem in public health leading to an estimated 4.95 million deaths in 2019. The selective pressure caused by the massive and repeated use of antibiotics has led to bacterial strains that are partially or even entirely resistant to known antibiotics...

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Autori principali:	Nina Compagne, Anais Vieira Da Cruz, Reinke T. Müller, Ruben C. Hartkoorn, Marion Flipo, Klaas M. Pos
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2023-01-01
Serie:	Antibiotics
Soggetti:	efflux pump inhibitor RND multidrug efflux pump Gram-negative bacteria antimicrobial resistance antibiotic resistance breakers AcrB
Accesso online:	https://www.mdpi.com/2079-6382/12/1/180
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