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Glyoxalase System as a Therapeutic Target against Diabetic Retinopathy

Hyperglycemia, a defining characteristic of diabetes, combined with oxidative stress, results in the formation of advanced glycation end products (AGEs). AGEs are toxic compounds that have adverse effects on many tissues including the retina and lens. AGEs promote the formation of reactive oxygen sp...

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Главные авторы: Gemma Aragonès, Sheldon Rowan, Sarah G Francisco, Wenxin Yang, Jasper Weinberg, Allen Taylor, Eloy Bejarano
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI AG 2020-10-01
Серии:Antioxidants
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Online-ссылка:https://www.mdpi.com/2076-3921/9/11/1062
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