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Impairment of glyoxalase-1, an advanced glycation end-product detoxifying enzyme, induced by inflammation in age-related osteoarthritis

Abstract Background Accumulation of advanced glycation end-products (AGEs) is involved in age-related osteoarthritis (OA). Glyoxalase (Glo)-1 is the main enzyme involved in the removal of AGE precursors, especially carboxymethyl-lysine (CML). We aimed to investigate the expression of several AGEs an...

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Detaylı Bibliyografya
Asıl Yazarlar: Sabine Trellu, Alice Courties, Stéphane Jaisson, Laëtitia Gorisse, Philippe Gillery, Saadia Kerdine-Römer, Carlos Vaamonde-Garcia, Xavier Houard, François-Paul Ekhirch, Alain Sautet, Bertrand Friguet, Claire Jacques, Francis Berenbaum, Jérémie Sellam
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2019-01-01
Seri Bilgileri:Arthritis Research & Therapy
Konular:
Online Erişim:http://link.springer.com/article/10.1186/s13075-018-1801-y
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