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Comparing Viral Vectors and Fate Mapping Approaches for Astrocyte-to-Neuron Reprogramming in the Injured Mouse Cerebral Cortex

Direct neuronal reprogramming is a promising approach to replace neurons lost due to disease via the conversion of endogenous glia reacting to brain injury into neurons. However, it is essential to demonstrate that the newly generated neurons originate from glial cells and/or show that they are not...

Celý popis

Uloženo v:
Hlavní autoři: Matteo Puglisi, Chu Lan Lao, Gulzar Wani, Giacomo Masserdotti, Riccardo Bocchi, Magdalena Götz
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2024-08-01
Edice:Cells
Témata:
astrocytes
neurons
direct reprogramming
fate mapping
birthdating
viral vectors
On-line přístup:https://www.mdpi.com/2073-4409/13/17/1408
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