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Redesigning a One‐Phase Enzymatic Assay to Streamline High‐Throughput Screening of Phytoene Desaturase Inhibitors

Abstract Phytoene desaturase (PDS) is an important target for the development of bleaching herbicides. The lack of the simple and efficient method to directly measure PDS enzyme activity has been the major hurdle to in vitro screening of potent PDS inhibitors. Here, we propose to substitute the trad...

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Principais autores: Zhilei Yu, Dejun Ma, Di Zhang, Ding Jia, Chunxue Wang, Han Xu, Zhen Xi
פורמט: Artigo
שפה:Inglês
יצא לאור: Wiley-VCH 2025-09-01
סדרה:ChemFoodChem
נושאים:
high‐throughput screening
molecular docking
one‐phase enzymatic reaction
PDS inhibitors
phytoene desaturase
גישה מקוונת:https://doi.org/10.1002/cfch.202500017
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