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Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation

Partial reprogramming by cyclic short-term expression of Yamanaka factors holds promise for shifting cells to younger states and consequently delaying the onset of many diseases of aging. However, the delivery of transgenes and potential risk of teratoma formation present challenges for in vivo appl...

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書誌詳細
主要な著者: Wayne Mitchell, Ludger JE Goeminne, Alexander Tyshkovskiy, Sirui Zhang, Julie Y Chen, Joao A Paulo, Kerry A Pierce, Angelina H Choy, Clary B Clish, Steven P Gygi, Vadim N Gladyshev
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications Ltd 2024-03-01
シリーズ:eLife
主題:
オンライン・アクセス:https://elifesciences.org/articles/90579
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