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Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation

Partial reprogramming by cyclic short-term expression of Yamanaka factors holds promise for shifting cells to younger states and consequently delaying the onset of many diseases of aging. However, the delivery of transgenes and potential risk of teratoma formation present challenges for in vivo appl...

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Principais autores: Wayne Mitchell, Ludger JE Goeminne, Alexander Tyshkovskiy, Sirui Zhang, Julie Y Chen, Joao A Paulo, Kerry A Pierce, Angelina H Choy, Clary B Clish, Steven P Gygi, Vadim N Gladyshev
פורמט: Artigo
שפה:Inglês
יצא לאור: eLife Sciences Publications Ltd 2024-03-01
סדרה:eLife
נושאים:
גישה מקוונת:https://elifesciences.org/articles/90579
תגים: הוספת תג
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