Aspirin and 5-Aminoimidazole-4-carboxamide Riboside Attenuate Bovine Ephemeral Fever Virus Replication by Inhibiting BEFV-Induced Autophagy

Recent study in our laboratory has demonstrated that BEFV-induced autophagy via activation of the PI3K/Akt/NF-κB and Src/JNK pathways and suppression of the PI3K-AKt-mTORC1 pathway is beneficial for virus replication. In the current study, we found that both aspirin and 5-aminoimidazole-4-carboxamid...

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Bibliografische gegevens

Hoofdauteurs:	Hsu-Hung Tseng, Wei-Ru Huang, Ching-Yuan Cheng, Hung-Chuan Chiu, Tsai-Ling Liao, Brent L. Nielsen, Hung-Jen Liu
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Frontiers Media S.A. 2020-11-01
Reeks:	Frontiers in Immunology
Onderwerpen:	5-aminoimidazole-4-carboxamide-1-β-riboside aspirin PI3K/Akt/NF-kB autophagy bovine ephemeral fever virus
Online toegang:	https://www.frontiersin.org/articles/10.3389/fimmu.2020.556838/full
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