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Pharmacometabolomics and mass spectrometry imaging approach to reveal the neurochemical mechanisms of Polygala tenuifolia

Polygala tenuifolia, commonly known as Yuanzhi (YZ) in Chinese, has been shown to possess anti-insomnia properties. However, the material basis and the mechanism underlying its sedative-hypnotic effects remain unclear. Herein, we investigated the active components and neurochemical mechanism of YZ e...

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Principais autores: Qian Li, Jinpeng Bai, Yuxue Ma, Yu Sun, Wenbin Zhou, Zhaoying Wang, Zhi Zhou, Zhonghua Wang, Yanhua Chen, Zeper Abliz
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2024-07-01
Serier:Journal of Pharmaceutical Analysis
Fag:
Polygala tenuifolia
Pharmaceutical metabolomics
Spatially resolved metabolome
Sedative-hypnotic
Neurochemical mechanisms
Online adgang:http://www.sciencedirect.com/science/article/pii/S2095177924000704
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