Pharmacometabolomics and mass spectrometry imaging approach to reveal the neurochemical mechanisms of Polygala tenuifolia

Polygala tenuifolia, commonly known as Yuanzhi (YZ) in Chinese, has been shown to possess anti-insomnia properties. However, the material basis and the mechanism underlying its sedative-hypnotic effects remain unclear. Herein, we investigated the active components and neurochemical mechanism of YZ e...

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Principais autores:	Qian Li, Jinpeng Bai, Yuxue Ma, Yu Sun, Wenbin Zhou, Zhaoying Wang, Zhi Zhou, Zhonghua Wang, Yanhua Chen, Zeper Abliz
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2024-07-01
Series:	Journal of Pharmaceutical Analysis
Assuntos:	Polygala tenuifolia Pharmaceutical metabolomics Spatially resolved metabolome Sedative-hypnotic Neurochemical mechanisms
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S2095177924000704
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