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Activated hepatic stellate cell-derived Bmp-1 induces liver fibrosis via mediating hepatocyte epithelial-mesenchymal transition

Abstract Liver fibrosis is a reparative response to injury that arises from various etiologies, characterized by activation of hepatic stellate cells (HSCs). Periostin, a secreted matricellular protein, has been reported to participate in tissue development and regeneration. However, its involvement...

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Bibliografiske detaljer
Principais autores: Sizhe Wan, Xianzhi Liu, Ruonan Sun, Huiling Liu, Jie Jiang, Bin Wu
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2024-01-01
Serier:Cell Death and Disease
Online adgang:https://doi.org/10.1038/s41419-024-06437-8
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