Single‐cell and spatial analyses reveal the association between gene expression of glutamine synthetase with the immunosuppressive phenotype of APOE+CTSZ+TAM in cancers

An immunosuppressive state is regulated by various factors in the tumor microenvironment (TME), including, but not limited to, metabolic plasticity of immunosuppressive cells and cytokines secreted by these cells. We used single‐cell RNA‐sequencing (scRNA‐seq) data and applied single‐cell flux estim...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Jinfen Wei, Wenqi Yu, Juanzhi Chen, Guanda Huang, Lingjie Zhang, Zixi Chen, Meiling Hu, Xiaocheng Gong, Hongli Du
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Wiley 2023-04-01
سلاسل:	Molecular Oncology
الموضوعات:	colorectal cancer GLUL immunosuppressive microenvironment metabolism single‐cell and spatial RNA‐seq tumor‐associated macrophages
الوصول للمادة أونلاين:	https://doi.org/10.1002/1878-0261.13373
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!