Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression.

It is known that genetic variants can affect gene expression, but it is not yet completely clear through what mechanisms genetic variation mediate this expression. We therefore compared the cis-effect of single nucleotide polymorphisms (SNPs) on gene expression between blood samples from 1,240 human...

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Detalhes bibliográficos

Principais autores:	Jingyuan Fu, Marcel G M Wolfs, Patrick Deelen, Harm-Jan Westra, Rudolf S N Fehrmann, Gerard J Te Meerman, Wim A Buurman, Sander S M Rensen, Harry J M Groen, Rinse K Weersma, Leonard H van den Berg, Jan Veldink, Roel A Ophoff, Harold Snieder, David van Heel, Ritsert C Jansen, Marten H Hofker, Cisca Wijmenga, Lude Franke
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2012-01-01
coleção:	PLoS Genetics
Acesso em linha:	http://europepmc.org/articles/PMC3261927?pdf=render
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